C47H73NO17, a preservative (antifungal, bactericide)

MME definition – “a drug used to treat fungus infections. Known allergy to this drug prohibits use. Side effects include blood clots, blood defects, kidney problems, nausea and fever. When used on the skin, allergic reactions canoccur.” Very often a most serious acute reaction after the infusion (1 to 3 hours later) is noted consisting of fever, shaking chills, hypotension, anorexia,nausea, vomiting, headache, dyspnea, and tachypnea. ephrotoxicity (kidney damage) is a major issue and can be severe and/or irreversible… Electrolyte imbalances (e.g. hypokalemia and hypocalcemia) may also occur. —Wiipedia.com

Chemical descriptions:

National Library of Medicine: PubChem
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5280965

Adverse effects
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Amphotericin%20B%2fadverse%20effects%22[Mesh%20Terms%3anoexp]

Toxicity
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Amphotericin%20B%2ftoxicity%22[Mesh%20Terms%3anoexp]

Poisoning
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Amphotericin%20B%2fpoisoning%22[Mesh%20Terms%3anoexp]

a.k.a. Fungilin®, Fungizone®, Abelcet®, AmBisome®, Fungisome®, Amphocil®, Amphotec® Ampho-Moronal, Amphotericin, Amphocin, Amphozone, Talsutin, Abelcet

 

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