Pertussis (Whooping Cough) Vaccines

//Pertussis (Whooping Cough) Vaccines
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Adverse Effects

Serious side-effects of pertussis vaccines are high-pitched screaming, persistent crying for 3 or more hours, fever over 103F, excessive sleepiness, convulsions or collapse/shock that may lead to either death or permanent brain damage. The only large study ever conducted in the U.S. to determine DPT vaccine reaction rates found that 1 in 875 DPT shots is followed by a convulsion or shock/collapse episode. The rate of permanent damage or death following DPT reactions is a hotly debated subject. One study surveying 215,000 Swedish children whom had received DPT shots showed a rate of permanent brain damage or death in 1 in 17,000 children.

Vaccination Could Not Survive in Free Market

Negative publicity generated by dissatisfied parents, documentaries and books led to a tremendous increase in the number of lawsuits filed against vaccine manufacturers. This resulted in low profit margins and for many manufacturers stopped producing the DTP vaccine by the early 1980s. By 1985, pharmaceutical companies had difficulty obtaining liability insurance. These multi-national corporations used their clout to lobby Congress for relief, and the government responded in 1986 by passing the National Childhood Vaccine Injury Act (NCVIA). Since then, tax dollars pay for vaccine-related damages and pharmaceutical companies are completely exempt from harm caused by their vaccine products.

Underestimated Figures

Many “authorities” rely on the 1981 British study, which reported that 1 in 110,000 DPT shots results in a serious neurological reaction and that permanent brain damage occurs in 1 in 310,000 shots. These figures are often misunderstood or misquoted as 1 in 110,000 children. But a child may receive 3 to 5 doses of vaccine, so this would be an error. In addition, high risk children were excluded from the study even though these categories of high-risk children are routinely vaccinated. Also, the study only counted those children who were hospitalized or who had a convulsion lasting 30 minutes or longer. Serious vaccine reactions can and do happen without hospitalization and convulsions lasting less than 30 minutes can still result in death or brain damage.

Unknown Vaccine Death Toll

It is not known how many pertussis vaccine deaths occur because often the deaths of babies, who receive DPT or DTaP shots and then die shortly after exhibiting classic pertussis vaccine reactions, are misclassified as SIDS. One SIDS study concluded that 17 of 23 vaccinated SIDS infants (or about 52%) died within one week of a DPT shot and 6 (or about 11%) died within 24 hours of the shot. A large, controlled study conducted by UCLA and the FDA showed that two babies in the study died following DPT injections, but their deaths were classified as sudden infant death syndrome (SIDS or crib death).

New and Improved?

The DTaP vaccine contains a purified acellular version of the pertussis vaccine and has fewer B. pertussis toxins in it. The DTaP vaccine is said to cause fewer reactions but this is questionable — and it’s still proven to cause injuries and death.

Pertussis More Benign

In its early stages, pertussis is indistinguishable from the many colds common in children and children may process the disease with little or no symptoms at all. Although whooping cough used to be a severe disease, in modern countries such as Europe and the U.S., whooping cough is much more manageable. This is due to improved sanitation, nutrition, and medical care (the use of antibiotics to control secondary infections; the employment of modern resuscitation methods and rehydration techniques). Washington State reported more than 160 cases 1984; there were no deaths, no cases of any serious consequences like brain damage. A vaccine is unnecessary.

Pertussis Persists Despite Near Universal Vaccination

Today between 2,000 and 10,000 cases of whooping cough are reported to the Centers for Disease Control (CDC) annually. However, there actually may be 40,000 to 100,000 cases each year because the CDC estimates that the disease is underreported in America by as much as 20 times. In 1984, Swedish epidemiologist B. Trollfors concluded that whole cell pertussis vaccines are only effective for 2 to 5 years. He pointed out that even countries with a 90-95 percent vaccination rate (such as the U.S.) could not completely prevent the disease.

Pertussis in Fully Vaccinated (Vaccine Failure)

In Washington State’s 160 cases of 1984, 49% (aged 3 months to 6 years of age) had been appropriately vaccinated with DPT. In 1993, Cincinnati reported that 40% of children who caught pertussis were vaccinated “appropriately.” The scientific literature is replete with evidence of vaccine failure. Review the documentation below to evaluate the vaccine’s effectiveness yourself.

 

Pertussis (Whooping Cough) Vaccines by Brand

DTCOQ/DTP Adsorbed Diphtheria, Tetanus, Pertussis Vaccine
Manufacturer Aventis
Microorganism
Licensed
Recommendations Start at two months of age, 3 injections at one or two month intervals.
Ingredients Aluminum hydroxide, Thimerosal, Diphtheria toxoid, Tetanus toxoid
Product Descriptions

Acel-P Pertussis
Manufacturer Wyeth-Ayerst
Microorganism The bacterial toxin of B. pertussis
Licensed New product in 2001, original license 1996
Recommendations 3 i.m. injections at 0, 6, 12 weeks (but not more than 10 weeks) in children 15 months to 6 years of age.
Ingredients Aluminum hydroxide, Gelatin, Polysorbate 80, Thimerosal, Pertussis toxin, Filamentous hemagglutinin (FHA), Aluminum phosphate
Product Descriptions

Zaantide Diptheria, tetanus and pertussis vaccine, adsorbed
Manufacturer Institute of Immunology (Croatia)
Microorganism C. diphtheria, C. tetani, B. Pertussis
Licensed
Recommendations Age 3-6 months; 0, 4-6 weeks, 4-6 weeks, 6 months.
Ingredients Formaldehyde, Thimerosal, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid
Product Descriptions

TRIVAX-AD (DT Per/Vac/Ads), Adsorbed Diphtheria, Tetanus and Pertussis Vaccine
Manufacturer The Wellcome Foundation Limited, London
Microorganism C. diphtheriae, C. tetani, B. pertussis
Licensed
Recommendations Not for adults and elderly. Children up to six years: 3 injections at intervals of not less than four weeks of age.
Ingredients Aluminum hydroxide, Thimerosal, Sodium chloride, Diphtheria toxoid, Tetanus toxoid, Sodium Borate, Succinic Acid
Product Descriptions

Tritanrix HepB (DTPw+HBV) Diphtheria (D), tetanus (T), pertussis (whole cell) (Pw) and hepatitis B (rDNA) (HBV) vaccine
Manufacturer GlaxoSmithKline
Microorganism C. diphtheriae, C. tetani, B. pertussis and hepatitis B virus
Licensed 07/19/1996 (E.U.)
Recommendations Three injections with an interval of at least one month between each.
Ingredients Thimerosal, Yeast, Sodium chloride, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Virus: Hepatitis B, Aluminum oxide
Product Descriptions

Tritanrix HB-HIB (DtwP, HBV, HiB) Diphtheria, tetanus, pertussis and hepatitis B
Manufacturer GlaxoSmithKline
Microorganism C. diphtheriae, C. tetani, B. pertussis and hepatitis B virus
Licensed 07/19/1996
Recommendations Single injection as early as 6 weeks of life.
Ingredients Aluminum hydroxide, Yeast, Sodium chloride, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Virus: Hepatitis B
Product Descriptions

Triple Antigen™ Diphtheria, Tetanus and Pertussis Vaccine (Adsorbed)
Manufacturer CSL Limited, New Zealand
Microorganism C. diphtheriae, C. tetani, B. pertussis
Licensed
Recommendations Triple Antigen™ should be given at 2, 4 and 6 months of age with a booster dose at 18 months of age.
Ingredients Thimerosal, Sodium chloride, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Sodium phosphate
Product Descriptions

Tripacel® Pertussis Vaccine-Acellular, Combined With Diphtheria And Tetanus Toxoids (Adsorbed)
Manufacturer Aventis
Microorganism Pertussis, Diphtheria, Tetanus
Licensed
Recommendations one dose administered at 2, 4 and 6 months of age, booster dose should be administered at 18 months of age, should not be administered to persons after their eighth birthday.
Ingredients Filamentous hemagglutinin (FHA), Pertactin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Pertussis Toxoid
Product Descriptions http://www.drugs.com/cons/TRIPACEL.html

TriHIBit® DTaP and Hib conjugate
Manufacturer Sanofi Pasteur
Microorganism The bacterial toxins C. diphtheriae, C. tetani, B. pertussis. and Haemophilus influenzae type b
Licensed 2001
Recommendations One, 0.5 mL i.m. injection of vaccine.
Ingredients Ammonium sulfate, Formaldehyde, Gelatin, Latex, Polysorbate 80, Pertussis toxin, Filamentous hemagglutinin (FHA), Aluminum potassium sulfate, Diphtheria toxoid, Tetanus toxoid, Haemophilus influenzae B
Product Descriptions

Tri-Immunol DPT Adsorbed
Manufacturer Wyeth (Canada)
Microorganism C. diphtheriae, C. tetani, B. pertussis
Licensed 07/24/1970
Recommendations The recommended vaccination schedule is a dose at 2 months, 4 months, 6 months and 15 or 20 months with a booster dose at prior to entering school at 4-6 years of age.
Ingredients Thimerosal, Tetanus, Aluminum phosphate
Product Descriptions http://www.vran.org/vaccines/dpt/dptr-tri-im93.htm#tri-im93

Tetravac® Diphtheria, tetanus, acellular pertussis and inactivated poliomyelitis vaccine, adsorbed
Manufacturer Aventis Pasteur
Microorganism
Licensed
Recommendations Primary immunisation can be given as 3 doses at an interval of 1-2 months starting at the age of 2 or 3 months or as 2 doses at an interval of 2 months starting at the age of 3 months and a third dose at the age of 12 months. A fourth dose should be administered within the second year of life.
Ingredients Aluminum hydroxide, Formaldehyde, Glutaraldehyde, 2 – Phenoxyethanol, Filamentous hemagglutinin (FHA), Diphtheria toxoid, Tetanus toxoid, Sodium hydroxide, Medium 199, Virus: polio, Acetic acid, Pertussis Toxoid
Product Descriptions Package insert

Tetramune (DTP-HbOC) Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed with Haemophilus b Conjugate Vaccine
Manufacturer Lederle Laboratories (Canada)
Microorganism C. diphtheriae, C. tetani, B. pertussis and Haemophilus b virus
Licensed 03/30/1993
Recommendations (Not for individuals age 7 or older) At 6 weeks of age, the immunisation series for TETRAMUNE consists of 3 doses of 0.5 mL each at approximately 2 month intervals, followed by a fourth dose of 0.5 mL at approximately 15 months of age.
Ingredients Formaldehyde, Thimerosal, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Sodium phosphate-monobasic, Sodium phosphate-dibasic dodecahydrate, Glycine, Potassium phosphate, Haemophilus influenzae B
Product Descriptions

TetrACT-HIB Adsorbed diphtheria, tetanus, pertussis, and conjugated haemophilus type b vaccine
Manufacturer Aventis Pasteur
Microorganism C. diphtheriae, C. tetani, B. pertussis and haemophilus type b virus
Licensed 06/03/2003
Recommendations 2 months of age, 3 injections at one or two month intervals.
Ingredients Aluminum hydroxide, Sucrose, Thimerosal, Sodium chloride, Diphtheria toxoid, Tetanus toxoid, Sodium hydroxide, Haemophilus influenzae B, Acetic acid, Trometamol, Potassium dihydrogen phosphate, Dehydrate sodium hydrogen phosphate
Product Descriptions Package insert

SII Triple Antigen Diphtheria, Tetanus and Pertussis Vaccine Adsorbed
Manufacturer Serum Institute of India, Ltd
Microorganism C. diphtheria, C. Tetani, B. Pertussis
Licensed 09/26/2006
Recommendations 3 doses should be inoculated on 3 separate occasions at 4 to 6 week intervals. The first dose should be given at approximately 6 weeks of age. Reinforcing injections should be given 12 months after the primary immunization and also between the ages of 4 to 6 years.
Ingredients Thimerosal, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid
Product Descriptions Website: http://www.seruminstitute.com/content/products/product_dtp_vac.htm

Repavax (dTaP/IPV) Diphtheria, Tetanus, Pertussis (Acellular, Component) and Poliomyelitis (Inactivated) Vaccine, adjuvanted
Manufacturer Aventis Pasteur
Microorganism C. diphtheriae, C. tetani, B. pertussis, polio virus
Licensed 09/26/2006
Recommendations from the age of three years, as a booster.
Ingredients Formaldehyde, Neomycin, 2 – Phenoxyethanol, Polymyxin B, Polysorbate 80, Streptomycin, Pertussis toxin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Virus: polio, Polyribosylribitol phosphate, African green monkey kidney cells
Product Descriptions Website: http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid=15256

QUADRACEL® (DTP, IPV) Diphtheria, tetanus, pertussis, adsorbed with poliomyelitis
Manufacturer Aventis
Microorganism C. Diphtheriae toxin, C. tetani toxin, B. pertussis, poliovirus type 1, 2, and 3
Licensed
Recommendations 4 i.m. injections at 2, 4, 6, and 18 months of age. Not recommended for those over 7 years of age.
Ingredients Formaldehyde, Neomycin, 2 – Phenoxyethanol, Polymyxin B, Polysorbate 80, Pertussis toxin, Filamentous hemagglutinin (FHA), Pertactin, Tetanus, Aluminum phosphate, Diphtheria toxoid, Bovine (cow) serum
Product Descriptions Package insert

POLIAcel™ Combination vaccine pack containing Act-HIB®: Haemophilus influenzae type b polysaccharide conjugated to tetanus protein reconstituted with QUADRACEL™: Pertussis Vaccine-Acellular Combined with Diphth
Manufacturer Aventis Pasteur
Microorganism C. diphtheriae, C. tetani, B. pertussis, polio virus and H. influenzae virus type b
Licensed
Recommendations primary immunisation schedule is one dose given at 2, 4 and 6 months of age. A booster dose may be given at 15 to 20 months of age.
Ingredients Formaldehyde, Glutaraldehyde, Neomycin, Polymyxin B, Polysorbate 80, Sucrose, Filamentous hemagglutinin (FHA), Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Bovine (cow) serum, Virus: polio, Haemophilus influenzae B, Trometamol, Pertussis Toxoid
Product Descriptions

Pentacel® (HiB, DPT, IPV) ActHIB® reconstituted with QUADRACEL®
Manufacturer Aventis (Canada)
Microorganism H. influenzae virus type b, C. diphtheriae, C. tetani, B. pertussis, and polio virus
Licensed 09/26/2005
Recommendations 4 injections at 2, 4, 6, and 18 months of age, not for use with persons age 7 or older.
Ingredients Formaldehyde, Neomycin, 2 – Phenoxyethanol, Polymyxin B, Polysorbate 80, Pertussis toxin, Filamentous hemagglutinin (FHA), Pertactin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Bovine (cow) serum, Virus: polio, Haemophilus influenzae B, Polyribosylribitol phosphate
Product Descriptions Package insert

Pediarix™ (HBV, DTaP, IPV) and inactivated Polio
Manufacturer GlaxoSmithKline
Microorganism C. diphtheriae, C. tetani and B. pertussis, H. influenzae virus type b and the polio virus
Licensed 12/13/2002
Recommendations 3 i.m. injections in infants as early as 6 weeks of age, to 7 years of age.
Ingredients Aluminum hydroxide, Formaldehyde, Neomycin, Polymyxin B, Polysorbate 80, Thimerosal, Yeast, Pertussis toxin, Filamentous hemagglutinin (FHA), Pertactin, Stopper vial may contain dry latex rubber, Tetanus, Sodium chloride, Virus: polio
Product Descriptions Package insert

Pediacel (DTaP, IPV, HiB) Diphtheria, tetanus, five component acellular pertussis, inactivated poliomyelitis and Haemophilus influenzae type b conjugate vaccine, adsorbed
Manufacturer Aventis Pasteur (Europe)
Microorganism C. diptheriae, C. tetani, B. pertussis, polio virus, H. influenzae B
Licensed 10/10/2002
Recommendations Three i.m. injections at 2, 3, 4 months with at least one month between injections.
Ingredients Aluminum hydroxide, Formaldehyde, Glutaraldehyde, Neomycin, 2 – Phenoxyethanol, Polymyxin B, Polysorbate 80, Streptomycin, Pertussis toxin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Virus: polio, Haemophilus influenzae B, Polyribosylribitol phosphate, African green monkey kidney cells
Product Descriptions Web site: http://emc.medicines.org.uk/emc/assets/c/html/displaydoc.asp?documentid=15257

Infanrix® (DTaP) Diphtheria and tetanus toxoids, acellular pertussis
Manufacturer GlaxoSmithKline
Microorganism The bacteria C. diphtheriae, C. tetani, B. pertussis
Licensed 01/29/1997
Recommendations For use as the initial four doses of the recommended diphtheria, tetanus, and pertussis vaccination series among children aged 6 weeks-6 years. Infanrix is also licensed for all remaining doses in the schedule for children who have received one or more doses of whole-cell DTP vaccine. Each dose of Infanrix contains 24 µg PT, 25µg FHA, 8µg Pn, 25 Lf of diphtheria toxoid, and 10 Lf of tetanus toxoid (Table 1).
Ingredients Aluminum hydroxide, Formaldehyde, Latex, 2 – Phenoxyethanol, Polysorbate 80, Pertussis toxin, Filamentous hemagglutinin (FHA), Pertactin, Sodium chloride, Diphtheria toxoid, Tetanus toxoid
Product Descriptions University: http://www.vaccinesafety.edu/components-DTaP.htm

Infanrix Hexa (DTaP, IPV, Hib, HBV) Diptheria, tetanus, pertussis, H. influenzae B, Hepatitis B and inactivated polio virus
Manufacturer GlaxoSmithKline (France)
Microorganism Diphtheria, tetanus, and pertussis toxoids, hepatitis B, Poliovirus Type 1 (Mahoney strain), Type 2 (MEF-1 strain), Type 3 (Saukett strain)
Licensed 10/26/2000
Recommendations Three i.m. injections at 2, 3, 4 months.
Ingredients Aluminum hydroxide, 2 – Phenoxyethanol, Pertussis toxin, Filamentous hemagglutinin (FHA), Pertactin, Sodium chloride, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid, Virus: Hepatitis B, Medium 199, Virus: polio, Haemophilus influenzae B, Lactose
Product Descriptions EMEA Document

Hexavac (DTaP, IPV, HBV, Hib) Diphtheria, tetanus, acellular pertussis, inactivated poliomyelitis, hepatitis B (recombinant) and Haemophilus influenzae type b conjugate vaccine, adjuvanted
Manufacturer Aventis Pasteur MSD
Microorganism C. Diphtheriae, C. tetani, B. pertussis, polio virus, hepatitis B and Haemophilus influenzae type b
Licensed 10/26/2000
Recommendations One i.m. injection for infants (from 2 to 12 months of age) with booster vaccination in toddlers (from 12 to 18 months of age).
Ingredients Aluminum hydroxide, Formaldehyde, Sucrose, Pertussis toxin, Filamentous hemagglutinin (FHA), Diphtheria toxoid, Tetanus toxoid, Bovine (cow) serum, Sodium hydroxide, Virus: Hepatitis B, Medium 199, Haemophilus influenzae B, Acetic acid, Trometamol, Sodium hydrogen carbonate, Potassium dihydrogen phosphate, Disodium phosphate dehydrate
Product Descriptions Suspension Press Release

DTAP-IPV Poliomyelitis
Manufacturer Statens Serum Institute
Microorganism C. diphtheriae, C. tetani, B. pertussis, polio virus, haemophilus influenzae type B virus
Licensed 01/29/1999
Recommendations Usually administered to babies at two, three and four months of age.
Ingredients Diphtheria toxoid, Tetanus toxoid, Virus: polio, Haemophilus influenzae B
Product Descriptions

DPT Merieux (DTPer/Vac/Ads) Adsorbed diphtheria tetanus and pertussis vaccine BP
Manufacturer Pasteur Mérieux
Microorganism
Licensed
Recommendations Three injections with an interval of at least 4 weeks between the first and second doses and at least 4 weeks between the second and the third doses. The vaccine may be administered to infants from 2 months of age.
Ingredients
Product Descriptions http://whale.to/vaccines/dtp_merieux.htm

DAPTACEL (DTaP)
Manufacturer Sanofi Pasteur
Microorganism The bacteria C. diphtheriae, C. tetani, B. pertussis
Licensed 2002
Recommendations 4 injections at 2, 4, 6 months, and 17-20 months of age.
Ingredients Formaldehyde, Glutaraldehyde, Latex, 2 – Phenoxyethanol, Pertussis toxin, Pertactin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid
Product Descriptions Package Insert

Certiva™ (DTaP) Diphtheria and tetanus toxoids and acellular pertussis vaccine, adsorbed
Manufacturer North American Vaccine, Inc.
Microorganism The bacterial toxins of C. diptheriae, C. tetani, and B. pertussis
Licensed 07/29/1998
Recommendations From 6 to 7 weeks, begin 3 i.m. injections at 2, 4, and 6 months of age, intervals of 6-8 weeks, with a fourth dose at 15-20 months, interval between 3rd and 4th doses should be at least 6 months.
Ingredients Ammonium sulfate, Aluminum hydroxide, Formaldehyde, Thimerosal, Pertussis toxin, Diphtheria toxoid, Tetanus toxoid, Bovine (cow) serum, Fetuin
Product Descriptions

Boostrix™ (Tdap) Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis, adsorbed
Manufacturer GlaxoSmithKline
Microorganism The bacterial toxins B. pertussis, C. tetani, C. diphtheriae
Licensed 12/29/2005
Recommendations For use in 10-18 year old persons; Single 0.5 mL i.m. injection route into the deltoid muscle of the upper arm.
Ingredients Formaldehyde, Latex, Polysorbate 80, Filamentous hemagglutinin (FHA), Pertactin, Aluminum adjuvant
Product Descriptions

Adacel™ Tetanus, reduced diphtheria toxoids, acelular pertussis, adsorbed (TdaP)
Manufacturer Sanofi Pasteur
Microorganism The bacterial toxins of C. dipthriae, C. Tetani, and B. Pertussis
Licensed 01/23/2006
Recommendations One i.m. injection for use in 11-64 year old persons
Ingredients Formaldehyde, Glutaraldehyde, 2 – Phenoxyethanol, Pertussis toxin, Filamentous hemagglutinin (FHA), Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid.
Product Descriptions

Acel-Immune Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed
Manufacturer Lederle Laboratories
Microorganism The bacterial toxins C. diphtheriae and C. tetani and acellular pertussis adsorbed
Licensed 12/30/1996
Recommendations Immunizations for Infants and Children under 7 Years of Age: The first three i.m. injections are usually given at ages 2, 4 and 6 months, the fourth dose at age 15-18 months, and the fifth dose at age 4-6 years. The fifth dose is not necessary if the fourth dose was given after the child’s fourth birthday. Immunizations for Children 7 or More Years of Age, Adolescents, and Adults: Three injections of Td; the first two doses should be given 4-8 weeks apart and the third dose 6-12 months after the second. Thereafter, routine booster doses of Td should be given every 10 years.
Ingredients Aluminum hydroxide, Formaldehyde, Gelatin, Polysorbate 80, Thimerosal, Pertussis toxin, Aluminum phosphate, Diphtheria toxoid, Tetanus toxoid.
Product Descriptions